美国Augusta University钱卓教授学术报告

发布者:系统管理员发布时间:2019-12-25浏览次数:13

报告题目:破译大脑

告人: 钱卓(Joe Tsien)教授,

   美国Augusta University

主持人: 谢维教授

时间:   202011010:00

地址:  榴园宾馆逸夫多功能厅


报告人介绍:

钱卓(Joe Tsien)教授是国际著名的脑科学家。他在麻省理工学院和普林斯顿大学开创的Cre-lox神经遗传技术,以及透导性和脑区特异性的基因或蛋白敲除和编辑技术,奠定了其在遗传与基因工程领域的开拓者地位。钱卓还是脑科学尤其是学习机理与神经网络研究方面的权威,被TIME杂志誉为“聪明鼠之父”。他的发表在Nature, Science, Cell, Neuron, Nat Neurosci等国际著名学术杂志上文章已被引用一万六千多次。他曾获得凯克基金会杰出学者奖、贝克曼奖、鲍劳斯.维康奖、美国华人杰出科学奖与美军首席科学家纪念勋章。

钱卓教授于2007年率先启动了Brain Decoding Project并担任其负责人,引发了欧洲美国目前的脑计划。他就大脑的设计与计算原理,提出了Theory of Connectivity,并在多种动物大脑、十几个脑区的神经网络中得到了验证。该理论将对新一代人工智能和机器人领域,尤其是人工通用智能和类脑芯片的研发,提供理论框架,具有指导意义。


报告题目:超级显微镜

  ——下一代的活体高时空分辨显微成像

报告人:陈良怡博士,北京大学博雅讲席教授

主持人: 谢维教授

时间:  202011011:00

地址:  榴园宾馆逸夫多功能厅

报告人介绍:

陈良怡博士为北京大学博雅讲席教授。近五年,围绕着糖尿病发病过程中胰岛素分泌异常机制这个关键科学问题,研究活体组织层次上的血糖调控紊乱、细胞层次上的细胞功能异常和分子层次上代谢如何调控囊泡分泌这三个具体问题,发展了一系列的高时空分辨率生物医学成像的可视化手段。发明高分辨率微型化双光子显微镜和双光子三轴扫描光片显微镜、多角度全内反射显微镜、低光毒超灵敏海森结构光超高分辨率显微镜等,解决生物学中的重要问题,成果发表在Nature Biotechnol, Nature Methods, Dev CellCell Res等杂志上,也入选“2018年中国光学十大进展”,“2017年中国科学十大进展”以及2018Nature Method年度方法“自由行为动物成像技术”等。


报告题目:A new approach for splicing analysis- potential and implications"

告人:Dr. Sureshkumar Balasubramanian

Associate Professor, School of Biological SciencesMonash University

主持人: 韩俊海教授

时间:  20201109:00

地址:  榴园宾馆逸夫多功能厅

报告人介绍:

Dr. Balasubramanian is interested in deciphering the mechanistic basis of genotype x environment interactions. His group focuses on three key areas. They are deciphering mechanisms through which plants sense and respond to changes in temperature using a combination of mutant analysis, natural variation and genomics. The second area is related to understanding molecular mechanisms of genetic diseases. Recently his group discovered a triplet repeat expansion associated genetic defect in Arabidopsis. Triplet expansions underlie several human genetic diseases such as Huntington's disease and Friedreichs ataxia. The Arabidopsis model shares striking similarities with the human situation at a molecular level. This provides an excellent genetic system to investigate fundamental aspects of repeat expansion associated genetic defects. They also have a particular interest in the analysis of splicing, trying to uncover the principles that govern splice site selection in organisms. To address these, they use a combination of model organisms such as Marchantia, Arabidopsis, fruit flies as well as humans. Their novel approach allows the determination of determinants of splice site selection and decipher the principles that govern splicing decisions. He published his work in many top journals such as Nature,Cell, Science, Nature Genetics, PNAS, PLoS Genetics, Current Biology, Plant Cellet al.






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